Genetic Control of Biochemical Reactions in Neurospora: An "Aminobenzoicless" Mutant

GENETICS: TATUMAND BEADLE GENETIC CONTROL OF BIOCHEMICAL REACTIONS IN NEURO- SPORA: AN "AMINOBENZOICLESS" MUTANT* By

Genetic Control of Biochemical Reactions in Neurospora.

One gene, one enzyme. What a simple concept, how obvious! This fundamental relationship between gene and gene product, hinted at by several previous investigators, did not become firmly established until George W. Beadle and Edward L. Tatum performed their pioneering analyses with Neurospora crassa. Prior to their proposing the one-gene–oneenzyme hypothesis, in the early 1940s, there was little...

"Genetic Control of Biochemical Reactions in Neurospora" (1941), by George W. Beadle and Edward L. Tatum

George Wells Beadle [7] and Edward Lawrie Tatum's 1941 article "Genetic Control of Biochemical Reactions in Neurospora [8]" detailed their experiments on how genes [9] regulated chemical reactions, and how the chemical reactions in turn affected development in the organism. Beadle and Tatum experimented on Neurospora, a type of bread mold, and they concluded that mutations to genes [9] affected...

development and implementation of an optimized control strategy for induction machine in an electric vehicle

in the area of automotive engineering there is a tendency to more electrification of power train. in this work control of an induction machine for the application of electric vehicle is investigated. through the changing operating point of the machine, adapting the rotor magnetization current seems to be useful to increase the machines efficiency. in the literature there are many approaches wh...

Biochemical, immunological, and genetic studies with a new type of tryptophan synthetase mutant of Neurospora crassa.

Previous studies have implicated indole-3glycerol phosphate as an intermediate in the biosynthesis of tryptophan in Escherichia coli (Yanofsky, 1956a, b) and Neurospora crassa (Yanofsky and Rachmeler, 1958; DeMoss, Imai, and Bonner, 1958; Suskind and Jordan, 1959). It has also been established that this compound is converted to tryptophan by the enzyme tryptophan synthetase in both organisms (D...